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Calculation of wall shear stress in left coronary artery bifurcation for pulsatile flow using two-dimensional

Sahid Smith1, Shawn Austin, G Dale Wesson

  • 1Department of Chemical Engineering & Biomedical Engineering, Florida A&M University, Tallahassee, FL 32310, USA.

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
|October 20, 2007
PubMed

Insights

Choosing the right blood viscosity model is crucial for accurate computational fluid dynamics (CFD) analysis of coronary artery blood flow and predicting heart disease risk. The generalized power law model is recommended for detailed hemodynamic studies.

Area of Science:

  • Cardiovascular Science
  • Biomedical Engineering
  • Fluid Dynamics

Background:

  • Coronary heart disease (CHD) development may be linked to hemodynamic forces within coronary arteries.
  • Understanding blood flow dynamics is essential for investigating CHD.
  • Hemodynamic shear stress is a key factor in arterial health.

Purpose of the Study:

  • To numerically examine pulsatile blood flow in the left coronary artery system.
  • To evaluate the impact of different blood viscosity models on computational fluid dynamics (CFD) simulations.
  • To determine the most appropriate model for analyzing blood flow and wall shear stress in coronary arteries.

Main Methods:

  • Utilized a triphasic waveform to simulate pulsatile blood flow.
  • Employed five non-Newtonian models and one Newtonian model to characterize blood's shear-thinning behavior.
  • Performed numerical simulations using computational fluid dynamics (CFD).

Main Results:

  • Blood viscosity model selection significantly impacts CFD results for blood velocity profiles in small arteries.
  • The generalized power law model is suggested as the preferred choice for simulating shear-thinning blood viscosity.
  • For analyzing wall shear stress (WSS) patterns, the Newtonian model may suffice, but not for determining WSS magnitude.

Conclusions:

  • Accurate CFD analysis of coronary artery blood flow requires careful selection of blood viscosity models.
  • The generalized power law model is recommended for studies focusing on blood velocity profiles and WSS magnitude.
  • Model choice is critical when investigating the role of WSS magnitude in coronary artery disease development.

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