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Updated: Jul 10, 2026

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
Published on: April 19, 2021
Inside-out NMR probe for portable spectrometry
Gaël Le Bec1, Kosai Raoof, Jean-Paul Yonnet
1Lab. des Images et des Signaux, ENSIEG, St Martin d'Heres, France. lebec@lis.inpg.fr
Portable Nuclear Magnetic Resonance (NMR) is feasible even in uneven magnetic fields. A novel single-sided probe design enables localized NMR spectrometry using a ferrite material construction.
Area of Science:
- Physics
- Chemistry
- Materials Science
Background:
- Nuclear Magnetic Resonance (NMR) measurements are typically limited by static magnetic field homogeneity.
- Achieving NMR in inhomogeneous fields requires overcoming specific theoretical and practical challenges.
Purpose of the Study:
- To propose and demonstrate a novel probe design for Nuclear Magnetic Resonance (NMR) measurements in inhomogeneous static magnetic fields.
- To enable portable and localized NMR spectrometry applications.
Main Methods:
- Design of a single-sided, inside-out NMR probe configuration.
- Utilizing perpendicular and correlated static and radiofrequency (RF) magnetic fields over a large volume.
- Construction of the probe using ferrite material.
Main Results:
- Demonstrated the feasibility of NMR measurements in grossly inhomogeneous static magnetic fields, provided inhomogeneity is below a theoretical limit.
- Successful construction of a single-sided inside-out NMR probe.
Conclusions:
- The proposed NMR probe design is effective for measurements in inhomogeneous fields.
- The ferrite-based probe is suitable for portable, localized NMR spectrometry.
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