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Updated: Jul 10, 2026

Transauricular Vagus Nerve Stimulation and Electroencephalographic Assessment in Disorders of Consciousness
Published on: July 11, 2025
Separation of subcortical component from cortical auditory evoked potential by independent component analysis
Hirokazu Takahashi1, Masayuki Nakao, Kimitaka Kaga
1Graduate School of Information Science and Technology, University of Tokyo, Japan. takahashi@u-tokyo.ac.jp
Abstract:
Auditory evoked potentials (AEPs) in the temporal cortex have typical slow positive/negative (P1/N1) biphasic waves, which are occasionally associated with an additional earlier small deflection (P0/N0). In the present paper, we attempted to address the neural origin of P0/N0 deflection by the independent component analysis (ICA) of densely mapped cortical AEPs of rats. The ICA results suggest that the deflection appears when subcortical contribution to AEP is equal to or larger than cortical contribution.

