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Updated: Jul 10, 2026
Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012
In-vivo lung cancer imaging in mice using 360 degrees free-space fluorescence molecular tomography
Nikolaos Deliolanis1, Tobias Lasser, Mark Niedre
1Laboratory for Bio-optics & Molecular Imaging, Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown 02129, USA.
Abstract:
We present the development and performance characteristics of a free-space fluorescence tomography system. The imaging system can capture complete angle projections of photons propagating through tissue in transillumination using a CCD camera. Experimental data on imaging lung cancer are presented. Overall, this imaging approach can offer unprecedented imaging performance in fluorescence molecular tomography of small animals.
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