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Updated: Jul 10, 2026

A Scanning Electron Microscopy-Compatible Optical Imaging Method for Mesoscopic All-Cell Brain Mapping
Published on: February 20, 2026
Combining optical imaging and computational modeling to analyze structure and function of living neurons
Bradley E Losavio1, G Duemani Reddy, Costa M Colbert
1Dept. of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA. blosavio@cns.bcm.tmc.edu
Abstract:
We are investigating the computational properties of principal neurons in the mammalian brain. To manage the small size and intricate structure of neuronal dendrites, we employ advanced optical imaging techniques in combination with automatic image reconstruction and computational modeling to study their complex spatio-temporal pattern of activity.
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