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Updated: Jul 10, 2026

Fibroblast Derived Human Engineered Connective Tissue for Screening Applications
Published on: August 20, 2021
A novel use for capillary channel fibers: enhanced engineered tissue systems
Karen J L Burg1, Douglas Brunson
1Clemson University, SC 29634, USA. kburg@clemson.edu
Abstract:
Capillary channel fibers (CCF) were selected for use in tissue engineering systems, due to their fluid wicking and cell guiding abilities. A study was conducted, comparing cell adhesion to CCF and mesh to traditional systems with fibers of round cross sectional area. A series of biochemical assays was conducted; the results indicated enhanced cellular attachment to the CCF based systems. Ongoing studies are being conducted to determine the rate of liquid diffusion within CCF reinforced tissue engineered composite systems.

