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A clinical and biochemical score for mortality prediction in patients with acute dyspnoea: derivation, validation and
A L Baggish1, D M Lloyd-Jones, J Blatt
1Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Background:
Risk stratification for patients with acute dyspnoea is a challenging task. No quantitative tool for mortality prediction among patients with acute dyspnoea is available.
Methods:
595 dyspnoeic subjects were enrolled in an emergency department. Clinical and biochemical factors independently predictive of death by 1 year were used to develop a mortality risk prediction tool.
Results:
Seven factors comprised the final tool: age (x0.3), heart rate (x0.2), blood urea nitrogen (x0.3), New York Heart Association class (x5), amino-terminal pro-B-type natriuretic peptide (NT-proBNP) >or=986 pg/ml (18 points), systolic blood pressure <100 mm Hg (11 points) and presence of a murmur (11 points). A continuous rise in mortality was seen from 1.7% in the lowest score quintile (n = 118; score
Conclusion:
A new risk stratification tool for acutely dyspnoeic patients has been derived and validated.
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