Related Experiment Video
Updated: May 23, 2026

07:11
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
[Detection of glaucomatous visual field defects using masking campimetry]
G Damm1, B J Lachenmayr, P M Vivell
1Universität-Augenklinik, München, Bundesrepublik Deutschland.
Summary
Noise-field campimetry shows 86% sensitivity in detecting visual field defects in ocular hypertension and glaucoma patients. However, its specificity is only 31%, making it unreliable for diffuse or small defects.
Area of Science:
- Ophthalmology
- Visual Neuroscience
- Medical Technology
Context:
- Ocular hypertension and glaucoma are leading causes of irreversible blindness.
- Accurate visual field testing is crucial for early detection and management.
- Comparing novel noise-field campimetry with standard light-sense perimetry is essential for evaluating diagnostic capabilities.
Purpose:
- To evaluate the diagnostic performance of noise-field campimetry compared to standard light-sense perimetry in patients with ocular hypertension and glaucoma.
- To assess the sensitivity and specificity of noise-field campimetry for detecting various types of visual field defects.
- To determine the agreement between noise-field campimetry and light-sense perimetry in characterizing the extent and location of visual field loss.
Summary:
- Noise-field campimetry demonstrated 86% sensitivity but only 31% specificity compared to light-sense perimetry in 100 eyes.
- The method reliably detects deep, localized nerve fiber bundle defects but is unreliable for small, relative, or diffuse visual field loss.
- Subjective agreement on defect extent and location varied from poor (41-46%) to moderate (32-34%) and good (22-25%) between the two methods.
Impact:
- Noise-field campimetry may serve as a supplementary tool for detecting specific glaucomatous defects.
- Limitations in detecting subtle visual field changes necessitate continued reliance on established perimetric techniques.
- Further research is needed to refine noise-field campimetry for broader clinical application in glaucoma diagnosis.
Related Concept Videos
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

