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Updated: Jan 20, 2026

Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs
Published on: January 27, 2023
Aspirin prophylaxis for thromboembolic disease after total joint arthroplasty
1Llanerch Medical Center, University of Pennsylvania, Havertown, Pennsylvania, USA.
Abstract:
The most appropriate prophylactic regimen for thromboembolic disease has not been determined. There appear to be several good alternatives, all of which yield similar results as determined by the incidence of symptomatic pulmonary embolism, but all are associated with various bleeding-related risks. Results from past research of almost 3500 total knee arthroplasties demonstrated a low risk for pulmonary emboli (0.1%) and a reduced risk for postoperative bleeding with use of aspirin and foot pumps as prophylaxis against thromboembolic disease. We continue to remain comfortable recommending this regimen for our patients.
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Structural Joints: Synovial Joints
Structural Joints: Fibrous Joints
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...

