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Cryptogenic organizing pneumonia in two patients with Behçet's disease
Y Nanke1, T Kobashigawa, T Yamada
1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan. ynn@ior.twmu.ac.jp
Clinical and Experimental Rheumatology
|November 14, 2007
Summary
Two women with Behçet
Area of Science:
- Pulmonology
- Rheumatology
- Internal Medicine
Background:
- Behçet's disease is a rare multisystem vasculitis.
- Pulmonary involvement in Behçet's disease is uncommon and can have a poor prognosis.
Observation:
- Two women, aged 37 and 40, presented with fever, cough, and pleuritic chest pain.
- Radiological imaging revealed ground glass opacities, peripheral nodular opacities, and consolidations.
- No thrombosis or aneurysm findings were noted.
Findings:
- Both patients were diagnosed with cryptogenic organizing pneumonia (COP) associated with Behçet's disease.
- Treatment with prednisolone (40-60 mg/day) resulted in clinical and radiological improvement in both cases.
Implications:
- This report highlights rare pulmonary manifestations of Behçet's disease.
- Early diagnosis and treatment of pulmonary parenchymal involvement are crucial for better outcomes.
- Further research is needed to fully understand and manage lung involvement in Behçet's disease.
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