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[MMR vaccine and egg allergy. Experience in a hospital immunization unit]

F Fina Avilés1, M Campins Martí, X Martínez Gómez

  • 1Servicio de Medicina Preventiva y Epidemiología, Hospital Universitario Vall d'Hebron, Universidad Autónoma de Barcelona, Barcelona, España.

Anales De Pediatria (Barcelona, Spain : 2003)
|October 24, 2007
PubMed

Insights

The measles, mumps, and rubella (MMR) vaccine is safe for children with egg allergies. This study found no significant adverse reactions in children with a history of egg allergy who received the MMR vaccine.

Area of Science:

  • Pediatric Allergy and Immunology
  • Vaccinology
  • Public Health

Context:

  • Egg allergy is a common concern for parents considering childhood vaccinations.
  • The measles, mumps, and rubella (MMR) vaccine is a critical public health tool.
  • Previous concerns existed regarding the safety of egg-derived vaccines in allergic individuals.

Purpose:

  • To evaluate the safety and reactogenicity of the measles, mumps, and rubella (MMR) vaccine in children with a history of egg allergy.
  • To present data from a prospective observational study conducted in a hospital immunization setting.
  • To assess adverse reactions following MMR vaccination in this specific pediatric population.

Summary:

  • A prospective study evaluated 121 children with egg allergy receiving the MMR vaccine.
  • While 75.7% of patients experienced reactions to egg ingestion, only mild local symptoms (17.8%) were observed post-MMR vaccination.
  • No significant adverse events were recorded, indicating a favorable safety profile.

Impact:

  • Provides evidence supporting the safe administration of the MMR vaccine to children with egg allergy.
  • Informs clinical practice guidelines for vaccinating allergic populations.
  • Contributes to maintaining high vaccination rates and preventing vaccine-preventable diseases.
Abstract

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