Related Experiment Video
Updated: Jul 10, 2026

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
Published on: July 1, 2013
[Traceability of a resorbable implant for lipoatrophy: why should it be traced and how should this be done? Example
C Dupont1, M Lafaurie, I Madelaine-Chambrin
1Service de pharmacie, hôpital Saint-Louis, APHP, 1, avenue Claude-Vellefaux, 75475 Paris cedex 10, France. clodupont@hotmail.com
Abstract:
Facial lipoatrophy is a frequent adverse effect of HIV-infected patients due to antiretroviral therapy. Intradermal injection of polylactic acid (Newfill) is one of the currently available treatments. Newfill is a resorbable implant and follow-up has to be rigorous. The Pharmacy and the Infectious Diseases units at the Saint-Louis hospital implemented a follow-up procedure. A follow-up of treated patients was made for 20 months. 127 patients were included. The rate of traceability was 100%. Such traceability is therefore feasible and will have to be implemented for the follow-up of patients treated with future filling products.

