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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

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Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging
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A brush stimulator for functional brain imaging.

V Jousmäki1, N Nishitani, R Hari

  • 1Brain Research Unit, Low Temperature Laboratory, Helsinki University of Technology, Brain Research Unit, Otakaari 3, 02015 HUT, Espoo, Finland. veikko@neuro.hut.fi

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
|October 24, 2007
PubMed
Summary
This summary is machine-generated.

A new non-magnetic tactile stimulator effectively records brain activity using magnetoencephalography (MEG). This device allows for real-life like stimulation to study the human somatosensory system.

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Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging

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Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Sensory Physiology

Background:

  • Magnetoencephalography (MEG) is a powerful tool for studying brain activity.
  • Non-magnetic stimulation methods are crucial for minimizing artifacts in MEG recordings.
  • Understanding the human somatosensory system requires precise and naturalistic stimulation techniques.

Purpose of the Study:

  • To introduce a novel, non-magnetic, hand-held tactile stimulator.
  • To evaluate the performance of this device in magnetoencephalography (MEG) recordings.
  • To explore its utility in functional magnetic resonance imaging (fMRI) experiments.

Main Methods:

  • A hand-held device utilizing an optic fiber bundle brush for tactile stimulation.
  • Modulated red light emission and reflectance detection for contact sensing.
  • Stimulation applied to the radial nerve innervation area on the back of the hand.

Main Results:

  • Clear somatosensory evoked responses observed in all 10 subjects.
  • Main deflections peaked 40-70 ms post-stimulus; earliest responses at 27-28 ms.
  • MEG source analysis localized neuronal activity to the primary somatosensory (SI) cortex with somatotopy.

Conclusions:

  • The developed device is feasible for MEG and fMRI studies.
  • Enables functional anatomy investigations of the human somatosensory system.
  • Offers new experimental possibilities for studying the human mechanoreceptor system.