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Related Concept Videos

Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
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In healthcare, informed consent is a crucial process that involves thoroughly communicating medical treatment options to patients, including benefits, risks, potential side effects, and alternatives. This process enables patients to make well-informed decisions about their care, ensuring they understand the implications of their choices before consenting to or refusing treatment.
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Related Experiment Video

Updated: Jul 10, 2026

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center
07:48

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center

Published on: January 9, 2026

Publication bias in surgery: implications for informed consent.

Dora Syin1, Tinsay Woreta, David C Chang

  • 1Center for Outcomes Research, Department of Surgery, John Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

The Journal of Surgical Research
|October 24, 2007
PubMed
Summary

Actual mortality rates for pancreatic surgery are 2.4 times higher than reported literature, especially in nonacademic centers. Informed consent should reflect these real-world risks for accurate patient understanding.

Related Experiment Videos

Last Updated: Jul 10, 2026

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center
07:48

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center

Published on: January 9, 2026

Area of Science:

  • Surgical Outcomes
  • Medical Data Analysis
  • Patient Safety

Background:

  • Literature suggests a 1-3% operative risk for pancreatic surgery.
  • These figures often derive from specialized centers and may not be generalizable.
  • Actual patient risk may differ significantly from published data.

Purpose of the Study:

  • To compare literature-based mortality rates for pancreatic surgery with actual in-hospital mortality.
  • To assess the generalizability of published pancreatic surgery outcomes.
  • To identify disparities in mortality rates between academic and nonacademic medical centers.

Main Methods:

  • A meta-analysis of major pancreaticoduodenectomy (PD) and total pancreatectomy (TP) studies (1998-2003).
  • Comparison with actual mortality data from a 20% sample of US hospital records (Nationwide Inpatient Sample).
  • Analysis stratified by academic versus nonacademic medical centers.

Main Results:

  • Literature mortality for PD and TP was 3.2% (16 studies, 3641 patients).
  • Actual mortality in the Nationwide Inpatient Sample was 7.6%, 2.4-fold higher than literature rates (P < 0.0001).
  • Nonacademic centers had a 11.4% mortality rate for PD, significantly higher than academic centers (6.4%) and literature rates.

Conclusions:

  • Real-world mortality for pancreatic resections is substantially higher than reported in academic literature.
  • Current literature-based risk estimates are not representative of actual surgical outcomes.
  • Informed consent must incorporate accurate, localized, and national mortality data for patient safety.