Related Experiment Video
Updated: Jul 10, 2026

Modified In Vivo Matrix Gel Plug Assay for Angiogenesis Studies
Published on: June 30, 2023
Essential factors associated with hepatic angiogenesis
Subir Kumar Das1, D M Vasudevan
1Department of Biochemistry, Amrita Institute of Medical Sciences, Elamakkara P.O. Cochin 682 026, Kerala, India. subirkumardas@aims.amrita.edu
Abstract:
Angiogenesis, the growth of new blood vessels, is essential during tissue repair. In contrast, uncontrolled angiogenesis promotes tumor. A balance between proangiogenic and antiangiogenic growth factors and cytokines tightly controls angiogenesis. With the identification of several proangiogenic molecules such as the vascular endothelial cell growth factor (VEGF), the fibroblast growth factors (FGFs), and the angiopoietins, and the recent description of specific inhibitors of angiogenesis such as platelet factor, angiostatin, endostatin, and vasostatin, it is recognized that therapeutic interference with vasculature formation offers a tool for clinical applications in various pathologies.
More Related Videos
08:53The Arteriovenous (AV) Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering
Published on: November 2, 2016
09:03Monitoring Functionality and Morphology of Vasculature Recruited by Factors Secreted by Fast-growing Tumor-generating Cells
Published on: November 23, 2014
Related Concept Videos
Regulation of Angiogenesis and Blood Supply
Mechanism of Angiogenesis
Liver Regeneration
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...
Role of Hematopoietic Growth Factors
Thrombopoietin (TPO), mainly released by the liver,...
Development of Blood Vessels
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...