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Updated: Jul 10, 2026

Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model

Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model

Published on: May 29, 2015

Erysipeloid cutaneous metastasis from bladder carcinoma.

Arianna Zangrilli¹, Rosita Saraceno, Loredana Sarmati

¹Department of Dermatology, University of Rome Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.

European Journal of Dermatology : EJD

|October 24, 2007

Summary

Cutaneous metastases from bladder cancer are rare in women. This case highlights an unusual erysipelas-like presentation on the thighs and groins, emphasizing early recognition of skin lesions in genitourinary cancers.

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Last Updated: Jul 10, 2026

Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model

Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model

Published on: May 29, 2015

Area of Science:

Oncology
Dermatology
Genitourinary Pathology

Background:

Cutaneous metastases from bladder cancer are infrequent, particularly in females.
Metastatic patterns can vary, but specific presentations are rare.

Observation:

A 56-year-old female with a history of bladder adenocarcinoma (T3N0M0) presented with skin lesions.
Lesions appeared as erythematous plaques with an erysipelas-like morphology.
The affected areas were the groins and thighs.

Findings:

Histopathology and immunohistochemistry confirmed the skin lesions as metastases from bladder carcinoma.
The erysipelas-like appearance and lower extremity location are exceptional features for bladder cancer metastasis.

Implications:

This case underscores the importance of recognizing unusual cutaneous manifestations of genitourinary malignancies.
Early diagnosis of skin metastases can be crucial for patient management and prognosis.
Highlights the need for a broad differential diagnosis in dermatology, including metastatic disease.