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Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
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The cadherins were one of the first cell adhesion molecules discovered; the term “cadherins”   is based on their calcium-dependent adhering properties. The first cadherins discovered on the epithelial, neuronal, and placental cells were named E-cadherin, P-cadherin, and N-cadherin, respectively. These classical cadherins share sequence and structural similarities. Other cadherins, including those involved in cell signaling, are grouped into non-classical cadherins. This diversity of cadherins...
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Coronary Artery Disease II: Pathophysiology

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Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
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Related Experiment Video

Updated: Jul 10, 2026

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium
09:33

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium

Published on: December 17, 2018

Arterial structure and function and environmental exposure to cadmium.

R Schutte1, T Nawrot, T Richart

  • 1Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Diseases, University of Leuven, Leuven, Belgium.

Occupational and Environmental Medicine
|October 24, 2007
PubMed
Summary

Higher cadmium body burden is linked to improved arterial health, showing lower pulse wave velocity and pressure, and increased femoral distensibility. This suggests cadmium exposure may paradoxically benefit arterial properties.

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Last Updated: Jul 10, 2026

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Removal of Trace Elements by Cupric Oxide Nanoparticles from Uranium In Situ Recovery Bleed Water and Its Effect on Cell Viability
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Published on: June 21, 2015

Area of Science:

  • Environmental Health
  • Cardiovascular Physiology
  • Toxicology

Background:

  • Cadmium toxicity is a growing concern, yet its impact on arterial properties remains understudied.
  • Understanding cadmium's effects on the vasculature is crucial for public health.
  • Arterial stiffness and function are key indicators of cardiovascular risk.

Purpose of the Study:

  • To investigate the association between lifetime cadmium exposure and arterial function.
  • To determine if cadmium body burden influences measures of arterial stiffness and distensibility.

Main Methods:

  • A population-based study involving 557 participants from areas with varying environmental cadmium exposure.
  • Measurement of 24-hour urinary cadmium excretion as an indicator of cumulative cadmium exposure.
  • Assessment of arterial properties including aortic pulse wave velocity, pulse pressures, and femoral distensibility and compliance.

Main Results:

  • Higher urinary cadmium excretion correlated with significantly lower aortic pulse wave velocity, brachial, and femoral pulse pressures.
  • Femoral distensibility and compliance were significantly higher in individuals with greater cadmium excretion.
  • These associations remained significant after adjusting for age and sex.

Conclusions:

  • Increased cadmium body burden is associated with improved arterial properties, including reduced arterial stiffness and enhanced distensibility.
  • The findings suggest a potentially protective effect of cadmium on the arterial system, contrary to general toxicological expectations.
  • Further research is warranted to elucidate the mechanisms behind these observed associations.