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Real-time Quaking-induced Conversion Assay for Detection of CWD Prions in Fecal Material
Published on: September 29, 2017
Applicability of current bovine spongiform encephalopathy (BSE) diagnostic procedures for chronic wasting disease
Kentaro Masujin1, Kimi Shimada, Kumiko M Kimura
1Prion Disease Research Center, National Institute of Animal Health, Tsukuba, Ibaraki 305-0856, Japan.
Abstract:
Chronic wasting disease (CWD) in cervids is one of the transmissible spongiform encephalopathies ; however, its risk to humans is still obscure. An increase in number of diseased deer in North America has raised concerns regarding the CWD risk to humans. We demonstrated that the con-firmatory procedures and the commercial diagnostic kits for bovine spongiform encephalopathy (BSE) can be adopted for the diagnosis of CWD. No CWD case was confirmed in the surveillance of 558 cervids that were examined between 2003 and 2006 in Japan.
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