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Slide Preparation Method to Preserve Three-dimensional Chromatin Architecture of Testicular Germ Cells
Published on: January 10, 2014
Sex chromosome complement regulates habit formation
Jennifer J Quinn1, Paul K Hitchcott, Elizabeth A Umeda
1Division of Molecular Psychiatry, Yale University, Connecticut Mental Health Center Abraham Ribicoff Research Facilities, 34 Park Street, New Haven, Connecticut 06508, USA.
Abstract:
Sex differences in brain function and behavior are regularly attributed to gonadal hormones. Some brain sexual dimorphisms, however, are direct actions of sex chromosome genes that are not mediated by gonadal hormones. We used mice in which sex chromosome complement (XX versus XY) and gonadal sex (ovaries versus testes) were independent, and found that XX mice showed faster food-reinforced instrumental habit formation than XY mice, regardless of gonadal phenotype.
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