Related Experiment Video
Updated: Jul 10, 2026

10:10
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
Retrobulbar hemodynamics and corneal surface temperature in glaucoma surgery
Fernando Galassi1, Barbara Giambene, Andrea Corvi
1Eye Clinic, University of Florence, viale Morgagni, Florence, 85-50134, Italy.
International Ophthalmology
|October 24, 2007
Summary
Glaucoma surgery improves blood flow in the eye and increases corneal surface temperature. Both deep sclerectomy and trabeculectomy showed similar positive effects on retrobulbar hemodynamics.
Area of Science:
- Ophthalmology
- Vascular Biology
- Surgical Innovation
Background:
- Glaucoma surgery aims to reduce intraocular pressure.
- Understanding the impact on ocular hemodynamics is crucial for patient outcomes.
- Corneal surface temperature (CST) changes may indicate vascular alterations.
Purpose of the Study:
- To investigate the effects of deep sclerectomy and trabeculectomy on retrobulbar hemodynamics.
- To assess changes in corneal surface temperature (CST) post-glaucoma surgery.
- To correlate hemodynamic changes with CST alterations.
Main Methods:
- 22 primary open-angle glaucoma eyes underwent deep sclerectomy; 19 underwent trabeculectomy.
- Color Doppler imaging (CDI) assessed ophthalmic artery (OA), central retinal artery (CRA), and short posterior ciliary arteries (SPCAs) velocities and resistance.
- Infrared thermography measured corneal surface temperature (CST).
Main Results:
- Both surgeries significantly increased end-diastolic velocity (EDV) and decreased resistivity index (RI) in OA, CRA, and SPCAs at 3 months.
- Corneal surface temperature (CST) significantly increased post-surgery in both groups.
- A negative correlation was observed between reduced RI in the OA and increased CST.
Conclusions:
- Deep sclerectomy and trabeculectomy demonstrate comparable efficacy in enhancing retrobulbar hemodynamics.
- Color Doppler imaging and infrared thermography are valuable tools for assessing vascular outcomes after glaucoma surgery.
- These findings suggest improved ocular blood flow and potential vascular regulation post-surgery.
Related Concept Videos
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...