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Updated: Jul 10, 2026

Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy
Published on: September 27, 2024
Endovascular therapy for chronic mesenteric ischemia
Gabriele Piffaretti1, Matteo Tozzi, Chiara Lomazzi
1Division of Vascular Surgery, Department of Surgery, University of Insubria, Ospedale di Circolo, Viale Borri 57, 21100, Varese, Italy. gabriele.piffaretti@tiscali.it
Endovascular therapy for chronic mesenteric ischemia offers effective treatment with high initial success rates. Midterm follow-up shows durable patency and symptom relief, indicating feasibility and acceptable outcomes.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Gastroenterology
Background:
- Chronic mesenteric ischemia (CMI) results from obstructive disease of the superior mesenteric artery (SMA) and celiac trunk.
- Endovascular therapy presents a minimally invasive alternative to traditional surgical interventions for CMI.
Purpose of the Study:
- To evaluate the effectiveness and durability of endovascular treatment for obstructive disease affecting the SMA and celiac trunk.
- To assess technical and clinical success rates, complication incidence, and long-term outcomes in patients with CMI.
Main Methods:
- Retrospective analysis of nine patients (15 lesions) treated for CMI.
- Data collection included technical/clinical success, complications, patency rates, and patient survival.
- Mean follow-up duration was 31 months.
Main Results:
- 100% primary technical and clinical success with no perioperative mortality.
- Two patients experienced major complications (pseudoaneurysms).
- Midterm patency rate was 78% at 2 and 5 years, with survival estimates of 85% and 68%, respectively. All patients reported symptom relief.
Conclusions:
- Endovascular treatment is a feasible option for chronic mesenteric arterial obstructive disease.
- The procedure demonstrates a low complication rate and acceptable midterm results.
- Sustained clinical benefit and patency support endovascular therapy for CMI.
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