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Related Experiment Video

Updated: Jul 10, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

Published on: July 28, 2020

Multiple subungual soft tissue metastases from a chondrosarcoma.

Leonhard E Ramseier1, Charles E Dumont, G Ulrich Exner

  • 1Department of Orthopedics Balgrist, University of Zurich, Zurich, Switzerland.

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery
|October 24, 2007
PubMed
Summary

Chondrosarcoma can spread to distant sites, including unusual subungual (under the nail) locations. This study reports on the surgical resection of a rare subungual chondrosarcoma metastasis.

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Area of Science:

  • Orthopedic Oncology
  • Skeletal Metastasis Research

Background:

  • Chondrosarcoma is a malignant tumor arising from cartilage cells.
  • Metastasis typically involves the lungs, progressing to other organs.
  • Skeletal metastases from chondrosarcoma are uncommon, with subungual involvement being exceptionally rare.

Observation:

  • A patient previously treated for foot chondrosarcoma presented with soft tissue metastases in digits.
  • Multiple metastases were noted in the fingers and toes.
  • A specific lesion was located beneath the fingernail (subungual).

Findings:

  • Subungual chondrosarcoma metastases represent an unusual clinical presentation.
  • No established evidence-based treatment guidelines exist for this specific condition.

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Last Updated: Jul 10, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
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Published on: July 28, 2020

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  • The affected finger lesion was treated with complete nail resection (RO).

    • Implications:

    • This case highlights the potential for chondrosarcoma to metastasize to unusual sites like the nail bed.
    • Surgical intervention, such as resection, may be a viable treatment option for localized subungual metastases.
    • Further research is needed to establish optimal treatment protocols for rare metastatic presentations of chondrosarcoma.