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Updated: Jul 10, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
Totally extracardiac Maze procedure performed on the beating heart
Andy C Kiser1, Gerhard Wimmer-Greinecker, W Randolph Chitwood
1Division of Cardiothoracic Surgery, Pinehurst Surgical Clinics, Pinehurst, North Carolina 28374, USA. akiser@pinehurstsurgical.com
A new vacuum-integrated radiofrequency ablation device simplifies the complex Cox Maze III procedure, enabling a totally extracardiac Maze (Ex-Maze) procedure. This novel approach mimics the gold standard Maze III pattern for improved atrial fibrillation treatment.
Area of Science:
- Cardiac Surgery
- Minimally Invasive Procedures
- Electrophysiology
Background:
- The Cox Maze III procedure is the gold standard for treating atrial fibrillation but is technically demanding.
- Complexity of the traditional Maze procedure limits its widespread adoption.
- Advancements in ablation technology are sought to simplify surgical approaches.
Purpose of the Study:
- To introduce a novel vacuum-integrated radiofrequency ablation device.
- To describe the totally extracardiac Maze (Ex-Maze) procedure developed using this device.
- To demonstrate how the Ex-Maze procedure mimics the Cox Maze III pattern.
Main Methods:
- Development of a vacuum-integrated radiofrequency ablation device.
- Performance of the totally extracardiac Maze (Ex-Maze) procedure.
- Application of ablation lines to isolate pulmonary veins, interconnect atria, and connect pulmonary veins to the inferior vena cava.
Main Results:
- The novel device facilitates a less complex surgical approach.
- The Ex-Maze procedure effectively replicates the ablation pattern of the Maze III procedure.
- Specific ablation lines were successfully created to achieve the desired atrial isolation and interconnection.
Conclusions:
- The totally extracardiac Maze (Ex-Maze) procedure, utilizing a novel vacuum-integrated radiofrequency ablation device, offers a simplified alternative to the Cox Maze III procedure.
- This technique maintains the efficacy of the gold standard Maze III pattern.
- Further evaluation of the Ex-Maze procedure's clinical outcomes is warranted.
Related Concept Videos
Cardiac Catheterization I: Pre-Procedure Overview
Cardiac Catheterization III: Left Heart Catheterization
