Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gene-environment interactions in asthma.

S McLeish1, S W Turner

  • 1Department of Child Health, University of Aberdeen, Aberdeen, UK.

Archives of Disease in Childhood
|October 24, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Managing magnets: An audit of introduction of the Royal College of Emergency Medicine Best Practice Guideline.

Acta paediatrica (Oslo, Norway : 1992)·2023
Same author

'They only smoke in the house when I'm not in': understanding the limited effectiveness of a smoke-free homes intervention.

Journal of public health (Oxford, England)·2020
Same author

Maternal vitamin D and E intakes during early pregnancy are associated with airway epithelial cell responses in neonates.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2015
Same author

ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2015
Same author

A systematic review of associations between environmental exposures and development of asthma in children aged up to 9 years.

BMJ open·2014
Same author

Prevalence and year-on-year trends in childhood thinness in a whole population study.

Archives of disease in childhood·2013
Same journal

Diagnostic accuracy study assessing the ability of paediatric asthma scores to predict admission following initial emergency department bronchodilator therapy: a Clinical Asthma Scoring systems in Paediatric Emergency (CASPER) study.

Archives of disease in childhood·2026
Same journal

Artificial intelligence for child health: current capabilities and the next frontier.

Archives of disease in childhood·2026
Same journal

Troubled origins and lasting impact of the first insulin injection.

Archives of disease in childhood·2026
Same journal

Paediatric readiness assessment tools in emergency care: a scoping review.

Archives of disease in childhood·2026
Same journal

Building a paediatric workforce to deliver the NHS prevention agenda: time for paediatric public health medicine?

Archives of disease in childhood·2026
Same journal

Impact of antenatal biological response modifying drugs on infant infection risk and vaccination rates: a national cohort study.

Archives of disease in childhood·2026
See all related articles

Asthma pathogenesis in children involves both genetic factors and environmental influences. Gene-environment interactions are crucial, but this field requires further research to answer many questions.

Area of Science:

  • Pediatric respiratory medicine
  • Immunology
  • Genetics

Background:

  • Asthma is a common chronic childhood disease with poorly understood origins.
  • Both genetic predisposition and Western lifestyle factors are implicated in asthma development.
  • Gene-environment interactions are increasingly recognized as significant contributors to asthma pathogenesis.

Purpose of the Study:

  • To review the existing evidence on gene-environment interactions in childhood asthma.
  • To synthesize findings from diverse populations regarding these interactions.
  • To highlight the current knowledge gaps in this rapidly evolving field.

Main Methods:

  • Literature review of studies investigating gene-environment interactions in pediatric asthma.
  • Synthesis of evidence from various ethnic and geographic populations.

Related Experiment Videos

  • Identification of key findings and areas for future research.

    • Main Results:

    • Accumulating evidence supports the role of gene-environment interactions in childhood asthma.
    • Studies have produced varied results across different populations.
    • The field is characterized by more questions than definitive answers.

    Conclusions:

    • Gene-environment interactions are vital in understanding childhood asthma.
    • Further research is needed to elucidate the complex interplay of genes and environment.
    • This review underscores the need for continued investigation into asthma pathogenesis.