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Garlic as an anti-fatigue agent
Naoaki Morihara1, Takeshi Nishihama, Mitsuyasu Ushijima
1Healthcare Research Institute, Wakunaga Pharmaceutical Co., Hiroshima, Japan. morihara_n@wakunaga.co.jp
Molecular Nutrition & Food Research
|October 24, 2007
Summary
Garlic shows promise as an anti-fatigue agent, with studies confirming its efficacy in improving physical and systemic fatigue. Further research is needed to fully understand its mechanisms and applications.
Area of Science:
- Nutritional Science
- Pharmacology
- Traditional Medicine
Background:
- Garlic's traditional uses are validated by over 3,000 publications.
- Garlic is traditionally used for fatigue, but mechanisms are unclear.
- Its anti-fatigue effects may stem from various biological and pharmacological properties.
Purpose of the Study:
- To explore the anti-fatigue effects of garlic.
- To investigate the influence of garlic processing on its efficacy.
- To summarize current evidence on garlic as an anti-fatigue agent.
Main Methods:
- Review of existing literature on garlic and fatigue.
- Analysis of animal studies demonstrating improved exercise endurance.
- Examination of human studies showing symptomatic improvement in fatigue.
Main Results:
- Garlic consumption improved exercise endurance in animal models.
- Specific processing methods, like aging raw garlic extract, enhance anti-fatigue effects.
- Human studies confirmed symptomatic relief from various types of fatigue.
Conclusions:
- Garlic is a promising agent for combating fatigue.
- Optimal processing methods enhance garlic's anti-fatigue potential.
- Further research is warranted to elucidate garlic's anti-fatigue mechanisms and applications.
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