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Updated: Jul 10, 2026

An R-Based Landscape Validation of a Competing Risk Model
Published on: September 16, 2022
Sample size calculations in the presence of competing risks
1Département de Biostatistique et Informatique Médicale, Hôpital Saint-Louis, Université Paris 7, Paris, France. aurelien.latouche@uvsq.fr
Abstract:
Recently, with the growth of statistical developments for competing risks analysis, some methods have been proposed to compute sample size in this context. These methods differ from a modelling approach: one is based on the Cox regression model for the cause-specific hazard, while another relies on the Fine and Gray regression model for the subdistribution hazard of a competing risk. In this work, we compare these approaches, derive a new sample size for comparing cumulative incidence functions when the hazards are not proportional (either cause-specific or subdistribution) and give practical advices to choose the approach best suited for the study question.
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