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Published on: August 7, 2017
Mothers' dietary patterns during pregnancy and risk of asthma symptoms in children at 3 years
N Fitzsimon1, U Fallon, D O'Mahony
1UCD School of Public Health and Population Science.
Insights
Maternal diet during pregnancy may influence childhood asthma risk. Higher intake of fruits, vegetables, and oily fish was linked to lower risk, while higher spreadable fat intake was associated with increased risk.
Area of Science:
- Pediatric Allergy and Immunology
- Nutritional Epidemiology
- Public Health
Background:
- Early life dietary factors are increasingly implicated in the development of childhood asthma.
- Understanding maternal dietary influences during pregnancy is crucial for asthma prevention strategies.
Purpose of the Study:
- To investigate the association between maternal dietary patterns during pregnancy and the risk of childhood asthma diagnosis by age 3.
- To analyze the impact of specific food groups on asthma aetiology in the Life-ways cohort.
Main Methods:
- Utilized a validated food frequency questionnaire to assess maternal dietary patterns during pregnancy.
- Analyzed general practitioner diagnosis records for asthma in 631 children up to age 3.
- Employed logistic regression models, adjusting for maternal lifestyle and socio-economic factors.
Main Results:
- A maternal diet rich in fruits, vegetables, and oily fish was associated with a reduced risk of childhood asthma.
- Higher maternal intake of spreadable fats correlated with an increased risk of asthma diagnosis in children.
- Asthma prevalence was 10.4%, consistent with existing epidemiological data.
Conclusions:
- Maternal dietary patterns during pregnancy appear to play a significant role in the aetiology of childhood asthma.
- Specific dietary components, such as fruits, vegetables, oily fish, and fats, may modulate asthma risk.
- Further research is needed to explore confounding factors and long-term effects of maternal diet on childhood respiratory health.
Abstract:
There is increasing evidence that dietary factors in early life play a role in the aetiology of childhood asthma. Our objective in this analysis was to assess whether maternal dietary patterns during pregnancy, as measured by a validated food frequency questionnaire, influenced general practitioner diagnosis of asthma by the age of 3 years in the Life-ways cohort of children. General Practice follow-up records were available for 631 of 1001 singleton children, twins having been excluded (63% follow-up rate). Overall 10.4% of children had diagnosed asthma, a prevalence rate comparable with other studies. In logistic regression models, based on quartiles of intake, which adjusted for maternal lifestyle and socio-economic circumstances, relatively higher maternal fruit and vegetable intake and oily fish consumption were associated with lower risk of children developing asthma, whilst those with relatively higher spreadable fat intake had a higher risk of asthma. These findings warrant further investigation as they imply an important role for maternal diet in childhood asthma, though the confounding effect of other social and lifestyle factors should be assessed as the children get older.
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