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Published on: March 11, 2016
[Hypertension: early detection of target organ damage]
Abigael Heim1, Antoine Pasche, François Feihl
1Division de physiopathologie, Département de médecine, CHUV et Université de Lausanne, 1011 Lausanne. Abigael.Heim@chuv.ch
Insights
Early detection of target organ damage is crucial for hypertensive patients. Screening for conditions like chronic kidney disease and cardiovascular issues aids in risk assessment and management.
Area of Science:
- Cardiology
- Nephrology
- Vascular Medicine
Context:
- Hypertension management requires early identification of target organ damage to assess cardiovascular risk.
- Current clinical practice emphasizes screening for cardiac and vascular complications in hypertensive individuals.
- Chronic kidney disease (CKD) is prevalent in hypertensive patients, particularly those over 55.
Purpose:
- To highlight the importance of early detection of target organ damage in hypertensive patients.
- To outline non-invasive methods for screening cardiovascular and vascular complications.
- To emphasize the significance of screening for chronic kidney disease and microalbuminuria.
Summary:
- Electrocardiography and echocardiography screen for left ventricular hypertrophy and ischemic heart disease.
- Non-invasive ultrasonography, pulse wave velocity, and ankle-arm index assess atherosclerosis and arteriosclerosis.
- Microalbuminuria serves as a marker for renal damage and a strong indicator of cardiovascular risk.
Impact:
- Facilitates comprehensive cardiovascular risk profiling in hypertensive patients.
- Enables timely intervention for organ damage, potentially preventing severe complications.
- Integrates renal health assessment into cardiovascular risk management strategies.
Abstract:
Early detection of target organ damage is essential in current clinical practice in order to establish the cardiovascular risk profile of hypertensive patients. Electrocardiogram and echocardiography allow the screening of left ventricular hypertrophy and ischemic heart disease. Atherosclerosis and arteriosclerosis can be searched for non-invasively by ultra-sonographic examination of large arteries, and by measurements of the pulse wave velocity and the ankle-arm index. Much emphasis needs to be put on screening for chronic kidney disease, which can be found at various stages in a majority of hypertensive patients aged 55 and over. Microalbuminuria should not only be regarded as a marker of renal damage, but also as a strong indicator of increased cardiovascular risk.
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