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Updated: Jul 10, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Differences in optical coherence tomography of the macula in advanced glaucoma and after a retinal artery occlusion
Rajesh K Shetty1, James P Boilling, Michael W Stewart
1Mayo Clinic, 4500 San Pablo Boulevard, Jacksonville, FL 32224, USA.
Background And Objective:
Optical coherence tomography (OCT) was used to evaluate the macular thickness in eyes with advanced glaucoma compared with eyes following a retinal artery occlusion.
Patients And Methods:
Ten patients with a retinal artery occlusion and 10 patients with severe glaucoma were evaluated with OCT using the macular thickness map protocol.
Results:
The median thinnest macular sector was 183 microns (range: 152 to 223 microns) in patients with glaucoma versus 143 microns (range: 98 to 177 microns) in patients with arterial occlusion (P = .001). Median macular volume was 5.9 mm3 (range: 5.1 to 6.7 mm3) in patients with glaucoma versus 5.1 mm3 (range: 3.6 to 6.1 mm3) in patients with arterial occlusion (P = .015).
Conclusions:
OCT demonstrates that patients with a retinal artery occlusion have significantly reduced macular thickness compared with those with severe glaucoma.
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