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Updated: Jul 10, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Perinatal depression: hiding in plain sight
Shari I Lusskin1, Tara M Pundiak, Sally M Habib
1New York University School of Medicine, New York, New York, USA. shari.lusskin@med.nyu.edu
Objective:
To promote prompt identification and treatment ofperinatal depression and enhance preventive care for women at risk.
Methods:
Using MEDLINE and PubMed searches, we reviewed the recent research on the origins, course, and consequences of pregnancy-related depression.
Results:
Depressive disorders are more common in pregnancy and postpartum than widely assumed, and there is no predictable protective effect of pregnancy. Relapse rates are high, and the postpartum period represents a time of increased vulnerability to depression.
Conclusion:
Early identification and treatment ofperinatal depression will minimize morbidity and mortality for the woman, the child, and the family.
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