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Sodium regulation of GAF domain function

M J Cann1

  • 1School of Biological and Biomedical Sciences, Durham University, South Road, Durham DH1 3LE, U.K. m.j.cann@durham.ac.uk

Biochemical Society Transactions
|October 25, 2007
PubMed
Summary

Sodium ions regulate cellular cyclic nucleotide levels by modulating GAF domains in both prokaryotic and eukaryotic organisms. This ancient mechanism controls adenylate cyclases and phosphodiesterases, impacting homeostasis.

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