Related Experiment Videos
Structure activity-based predictive toxicology: an efficient and economical method for generating non-congeneric data
H S Rosenkranz1, N Takihi, G Klopman
1Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, PA 15261.
Mutagenesis
|September 1, 1991
Abstract:
Starting with the results of the mutagenicity of 100 chemicals, we use CASE, a structure activity relational system, to select additional chemicals for inclusion into a data base. We demonstrate that a data base consisting of approximately 180 carefully selected chemicals is as predictive as the analysis based upon 820 'unselected' chemicals.