Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Micturition Reflex01:26

The Micturition Reflex

Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating urine...
Urodynamic Studies: Uroflowmetry01:19

Urodynamic Studies: Uroflowmetry

Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...
Physiology of the Genitourinary System III: Urine Concentration and Dilution01:20

Physiology of the Genitourinary System III: Urine Concentration and Dilution

The kidneys concentrate or dilute urine to maintain water and electrolyte balance. Nephrons, particularly the loop of Henle, play a crucial role in this process through the countercurrent multiplication system. This system establishes a high osmolarity in the renal medulla, which is essential for water reabsorption. In the loop of Henle’s descending limb, water is reabsorbed into the surrounding medulla due to its permeability to water. In contrast, the ascending limb actively transports...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reasons for introducing self-intermittent urinary catheterization and long-term outcomes in individuals with multiple sclerosis: a retrospective study.

World journal of urology·2026
Same author

Urodynamic Voiding Patterns in Multiple Sclerosis.

Neurourology and urodynamics·2026
Same author

Long-term intermittent catheterization: Safety and outcomes from a prospective observational study.

BJUI compass·2026
Same author

Complications and Risk Factors of Neurogenic Bladder: A Delphi Consensus.

European urology open science·2026
Same author

Bladder diary in neuro-urology: feasibility, usefulness, and reasons for no completion.

World journal of urology·2025
Same author

Correction: Clinical and urodynamic benefit of adding antimuscarinics after a loss of efficacy of intradetrusor botulinum toxin in patients with multiple sclerosis.

World journal of urology·2025

Related Experiment Video

Updated: Jul 10, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
03:26

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Decrease in urethral pressure following repeated cough efforts: a new concept for pathophysiology of stress urinary

Xavier Deffieux1, Katelyne Hubeaux, Raphaël Porcher

  • 1Pierre & Marie Curie University; Urodynamics Laboratory, Rothschild Hospital, AP-HOP, 33 boulevard de Picpus, Paris Cedex 12, France. x.deffieux@free.fr

International Journal of Urology : Official Journal of the Japanese Urological Association
|October 25, 2007
PubMed
Summary

Repeated coughing significantly decreases maximum urethral closure pressure (MUCP) in women with stress urinary incontinence (SUI). This finding suggests potential periurethral muscle fatigue as a cause for SUI.

More Related Videos

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
03:25

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Published on: June 16, 2022

Related Experiment Videos

Last Updated: Jul 10, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
03:26

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
03:25

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Published on: June 16, 2022

Area of Science:

  • Urology
  • Gynecology
  • Pelvic Floor Disorders

Background:

  • Stress urinary incontinence (SUI) is a common condition affecting women.
  • Maximum urethral closure pressure (MUCP) is a key urodynamic parameter.
  • The effect of repeated coughs on MUCP in SUI patients is not fully understood.

Purpose of the Study:

  • To investigate the change in MUCP after repeated coughs in women with SUI.
  • To compare MUCP response to coughs between women with and without SUI.

Main Methods:

  • MUCP was measured at rest and after seven cough efforts.
  • Seventy women under 40 were studied, including 47 with SUI and 23 without.
  • Urodynamic investigation was performed.

Main Results:

  • A decrease in MUCP exceeding 20% after seven coughs was observed in 38% of SUI patients.
  • Only 4% of non-SUI women showed a similar decrease in MUCP (P = 0.0069).
  • High repeatability (ICC=0.94) of MUCP measurements was noted.

Conclusions:

  • A significant decrease in MUCP following repeated coughs is common in women with SUI.
  • Periurethral muscle fatigue is a potential contributing factor to this phenomenon.
  • These findings highlight the impact of repetitive stress on urethral function in SUI.