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Rapid Generation of Amyloid from Native Proteins In vitro
05:48

Rapid Generation of Amyloid from Native Proteins In vitro

Published on: December 5, 2013

The geometry of alpha-sheet: Implications for its possible function as amyloid precursor in proteins

Steven Hayward1, E James Milner-White

  • 1School of Computing Sciences, University of East Anglia, Norwich NR4 7TJ, United Kingdom. sjh@cmp.uea.ac.uk

Proteins
|October 25, 2007
PubMed
Summary

Alpha-sheet structures, key to amyloid formation, are helical and untwisted, facilitating larger, more stable stacks than beta-sheets. These "mirror" structures offer insights into protein aggregation.

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