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Updated: Jul 10, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

[Antibiotics in current infections]

P Semaille1

  • 1D.M.G.--U.L.B.

Revue Medicale De Bruxelles
|October 26, 2007
PubMed

Insights

Antibiotic resistance is a growing concern. Prescribing antibiotics judiciously, considering patient factors and evidence, is crucial to combatting bacterial resistance and reducing selection pressure.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Pharmacology

Context:

  • The rise of antibiotic resistance poses a significant threat to public health.
  • Antibiotic use in general practice requires careful consideration of various influencing factors.

Purpose:

  • To discuss factors contributing to antibiotic resistance.
  • To outline appropriate antibiotic indications in current infections.
  • To emphasize the importance of clinical expertise in antibiotic prescribing.

Summary:

  • This article examines the emergence and increase of bacterial antibiotic resistance.
  • It explores factors influencing resistance and current antibiotic indications in general practice.
  • Integrating patient characteristics, clinical exams, and literature evidence is key for optimal antibiotic prescription.

Impact:

  • Reducing the selection pressure exerted on bacteria by optimizing antibiotic prescriptions.
  • Improving patient outcomes through evidence-based antibiotic selection.
  • Contributing to antimicrobial stewardship efforts to preserve antibiotic efficacy.

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