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Updated: Jul 10, 2026
11:17
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Summary
Antibiotic resistance is a growing concern. Prescribing antibiotics judiciously, considering patient factors and evidence, is crucial to combatting bacterial resistance and reducing selection pressure.
Area of Science:
- Microbiology
- Infectious Diseases
- Pharmacology
Context:
- The rise of antibiotic resistance poses a significant threat to public health.
- Antibiotic use in general practice requires careful consideration of various influencing factors.
Purpose:
- To discuss factors contributing to antibiotic resistance.
- To outline appropriate antibiotic indications in current infections.
- To emphasize the importance of clinical expertise in antibiotic prescribing.
Summary:
- This article examines the emergence and increase of bacterial antibiotic resistance.
- It explores factors influencing resistance and current antibiotic indications in general practice.
- Integrating patient characteristics, clinical exams, and literature evidence is key for optimal antibiotic prescription.
Impact:
- Reducing the selection pressure exerted on bacteria by optimizing antibiotic prescriptions.
- Improving patient outcomes through evidence-based antibiotic selection.
- Contributing to antimicrobial stewardship efforts to preserve antibiotic efficacy.
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00:57Antibiotic Selection
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Such synergistic combinations...
Such synergistic combinations...