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Updated: Jul 10, 2026

Induction of Complete Transection-Type Spinal Cord Injury in Mice
Published on: May 6, 2020
Spinal cord transection for definitive untethering of repetitive tethered cord
Jeffrey P Blount1, R Shane Tubbs, John C Wellons
1Section of Pediatric Neurosurgery, University of Alabama at Birmingham and Children's Hospital, Birmingham, Alabama 35233, USA.
Abstract:
In certain highly selected circumstances, division of a distally nonfunctional or dysfunctional cord can be a means of definitive untethering that spares and protects more rostral neurological function and results in definitive untethering. The authors reviewed their institutional experience with such cases and evaluated the limited literature. Based on their experience, treatment can be effective in carefully selected patients who undergo spinal cord transection, and the rate of repetitive tethered spinal cord can be decreased.

