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Related Experiment Video

Updated: Jul 10, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

[Focal epithelial hyperplasia].

E Vera-Iglesias¹, M García-Arpa, P Sánchez-Caminero

¹Servicio de Dermatología. Hospital General de Ciudad Real. España. everaigl@hotmail.com

Actas Dermo-Sifiliograficas

|October 27, 2007

Summary

Focal epithelial hyperplasia, a rare oral condition caused by human papilloma virus (HPV), presents as benign growths. This case highlights HPV serotype 13 in a young Ecuadorian patient, expanding geographic and demographic understanding.

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Glomerular Outgrowth as an Ex Vivo Assay to Analyze Pathways Involved in Parietal Epithelial Cell Activation

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Published on: August 19, 2020

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Last Updated: Jul 10, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Glomerular Outgrowth as an Ex Vivo Assay to Analyze Pathways Involved in Parietal Epithelial Cell Activation

Glomerular Outgrowth as an Ex Vivo Assay to Analyze Pathways Involved in Parietal Epithelial Cell Activation

Published on: August 19, 2020

Area of Science:

Oral pathology
Viral infections
Dermatology

Background:

Focal epithelial hyperplasia (FEH) is a rare oral mucosal condition linked to human papilloma virus (HPV).
FEH typically manifests as benign epithelial growths, predominantly on the lower lip.
The condition shows a racial predilection, being more common in Native Americans and Eskimos, and is associated with HPV serotypes 13 and 32.

Observation:

A case study of a 17-year-old female patient from Ecuador is presented.
The patient exhibited multiple papular lesions on both lips.
Clinical and histological examinations confirmed the diagnosis of focal epithelial hyperplasia.

Findings:

Polymerase chain reaction (PCR) analysis was performed on the lesions.
HPV serotype 13 was detected in the patient's oral lesions.
This finding supports the association of HPV 13 with FEH in a diverse geographic and ethnic population.

Implications:

This case expands the known geographic distribution of focal epithelial hyperplasia.
It underscores the role of HPV serotype 13 in the etiology of FEH across different populations.
Highlights the importance of considering HPV in the differential diagnosis of oral papular lesions.