Related Experiment Video
Updated: Jul 10, 2026

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
Published on: June 28, 2024
Preconceptional folic acid utilization in Israel: five years after the guidelines
Yona Amitai1, Nirah Fisher, Hana Meiraz
1Department of Maternal, Child and Adolescent Health, Ministry of Health, 20 King David St., Jerusalem 91010, Israel.
Objective:
In Israel, a national survey was conducted in order to assess the efficacy of the ongoing national folic acid (FA) campaign launched in 2000. The Ministry of Health had issued official guidelines in August 2000 recommending daily FA supplementation for all childbearing age women.
Methods:
In 2005, structured interviews of pregnant and postpartum women were conducted by the nursing staff of the Maternal Child Health Clinics administered by the Public Health Service. The results of the 2005 survey are compared with similar surveys done in 2002 and 2000 (baseline).
Results:
In the 2005 survey (n=1860), FA awareness, knowledge, timing knowledge and preconceptional utilization were 90.3%, 80.8%, 74.6% and 34.0%, respectively. Education was significantly associated with compliance: only 13.6% of women with <12 years of education utilized FA preconceptionally versus 48.1% of women with >or=16 years. In the 2002 survey (n=1661), FA awareness, knowledge, and preconceptional utilization were 85%, 77.7% and 30.5%, respectively. In the 2000 survey (n=1719), FA awareness was 54.6%, knowledge was 17.6% and preconceptional utilization was 5.2%.
Conclusions:
The national preconceptional FA campaign in Israel has resulted in significant increases in awareness, knowledge and preconceptional utilization.
Related Concept Videos
Teratogenicity
Cancer Prevention
Some...
In Vitro Fertilization
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
Preventive Healthcare Services
Bioavailability Study Design: Healthy Subjects Versus Patients
Drug Dosing: Infants and Children
