Advanced cervical squamous cell carcinoma with skin metastasis

Area of Science:

• Gynecologic Oncology
• Dermatology
• Oncology

Background:

• Cervical cancer is a common gynecologic malignancy.
• Skin metastasis as an initial sign of recurrence or persistence is exceptionally rare.

Observation:

• A 72-year-old woman with FIGO stage IIB cervical squamous cell carcinoma presented with widespread erythematous skin lesions one year post-treatment.
• Biopsy confirmed metastatic squamous cell carcinoma.
• Imaging revealed disseminated disease involving lungs and bone.

Findings:

• Skin metastasis in this case was a late manifestation.
• The patient experienced rapid progression of visceral disease despite palliative chemotherapy.
• The patient died 6 months after the onset of skin lesions.

Implications:

• This case highlights skin metastasis as a significant indicator of advanced and uncontrolled cervical cancer.
• Early recognition of skin lesions in cervical cancer patients is crucial for prognosis assessment.
• Such presentations warrant thorough investigation for disseminated disease.