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Published on: November 7, 2017
Cardiorenal anemia syndrome in chronic kidney disease
1Department and Institute of Physiology, National Yang-Ming University, Taipei, Taiwan, ROC. dctarng@vghtpe.gov.tw
Insights
Anemia is common in chronic kidney disease (CKD) and worsens with declining kidney function. Early diagnosis and treatment of anemia in CKD patients can improve quality of life and potentially slow disease progression.
Area of Science:
- Nephrology
- Hematology
- Internal Medicine
Background:
- Anemia is a common complication of chronic kidney disease (CKD), often progressing as renal function declines.
- CKD patients with diabetes and hypertension face increased mortality risk due to anemia.
- Anemia in CKD is frequently diagnosed late or undertreated, even after renal replacement therapy initiation.
Purpose of the Study:
- To provide recommendations for the early diagnosis and management of anemia associated with CKD.
- To emphasize the importance of timely anemia treatment in high-risk CKD patients with cardiovascular diseases.
- To align clinical practice with international guidelines for managing CKD-related anemia.
Main Methods:
- Review and synthesis of international practice guidelines on anemia in CKD.
- Analysis of current literature on the impact of anemia on CKD progression and patient outcomes.
- Development of practical recommendations for diagnosis and treatment thresholds.
Main Results:
- Anemia significantly impacts quality of life and mortality in CKD patients.
- Early detection and intervention for anemia in CKD are crucial for better patient outcomes.
- Current recommendations suggest maintaining hemoglobin levels at or above 11 g/dL.
Conclusions:
- Anemia of CKD requires earlier diagnosis and appropriate management to mitigate risks.
- Optimizing anemia treatment in CKD may improve patient quality of life and delay end-stage renal disease.
- Adherence to established guidelines is essential for effective CKD-related anemia care.
Abstract:
Anemia is a frequently encountered problem of chronic kidney disease (CKD) and deteriorates as renal function declines. Anemia increases the risk of death in CKD patients with diabetes and hypertension, which are the 2 leading causes of CKD. Recent studies suggest that correction of anemia improves patient quality of life and may delay the progression to end-stage renal disease. Anemia is often only treated in the late stages of CKD or after the initiation of renal replacement therapy. Thus, anemia of CKD is often unnoticed and lacks appropriate treatment. To practically manage high-risk patients with CKD and its associated cardiovascular diseases, it is mandatory to diagnose and appropriately treat anemia of CKD earlier. The optimal level of hemoglobin for greatest clinical benefit is unclear, but at present, it is recommended to remain > or = 11 g/dL. This paper provides recommendations for the diagnosis and management of anemia associated with CKD based on international practice guidelines.
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