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Mechanical Dissociation of Tissues for Single Cell Analysis Using a Motorized Device

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Published on: November 10, 2023

Discarded cellular components and the technical efficiency of component preparation.

Marketta Veihola¹, Pekka Aroviita, Riitta Kekomäki

¹Finnish Red Cross Blood Service, Kivihaantie 7, 00310 Helsinki, Finland. marketta.veihola@bts.redcross.fi

The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care

|October 27, 2007

Summary

Blood banking efficiency improves with lower discard rates of red blood cells (RBCs) and platelets (PLTs). Data envelopment analysis (DEA) highlights that accounting for discarded components is crucial for accurate efficiency assessments.

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Area of Science:

Health Services Research
Operations Research
Blood Banking and Transfusion Medicine

Background:

Increasing cost pressures necessitate improvements in blood banking production efficiency.
Technical efficiency in blood collection and processing is vital for resource optimization.
Discard rates of blood components impact overall operational effectiveness and cost.

Purpose of the Study:

To investigate the relationship between discard rates and technical efficiency in blood banking.
To assess the impact of discarded blood components on efficiency metrics.
To inform strategies for enhancing the production chain of collected blood.

Main Methods:

Data envelopment analysis (DEA) was employed to model technical efficiency.
Included whole-blood (WB) collections, aphaeresis-platelets, and discarded red blood cells (RBCs) and platelets (PLTs).
Analyzed the correlation between discard proportions and efficiency scores.

Main Results:

Technical efficiency tended to be higher when the proportion of RBC and PLT discards from WB collections was lower.
DEA models demonstrated that including discarded components significantly affects efficiency outcomes.
Lost production output from discards represents a quantifiable monetary value.

Conclusions:

Minimizing discard rates is essential for improving technical efficiency in blood banking.
Discarded blood components must be incorporated into efficiency analyses for accurate evaluation.
Optimizing the blood collection and processing chain can mitigate costs and enhance resource utilization.