Stress echocardiography for risk stratification of asymptomatic patients with type 2 diabetes mellitus
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Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Suzanne Fateh-Moghadam1, Thomas Reuter, Patrik Htun
1Medizinische Klinik mit Schwerpunkt Kardiologie, Universitätsklinik Charité-Campus Virchow, Humboldt-Universität zu Berlin und Freie Universität Berlin, Germany. suzanne.fateh-moghadam@charite.de
Background:
The purpose of this study was to assess stressechocardiography (SE) for risk stratification of asymptomatic type 2 diabetic patients (DM2) without known coronary artery disease CAD.
Methods:
A total of 211 consecutive, asymptomatic DM2 patients underwent exercise (n=177) or dobutamine (n=34) SE and were followed up for 11+/-2 months. Primary endpoint was a major cardiac or vascular event (MACCE; all-cause-death, non-fatal myocardial infarction, coronary revascularization procedures, cerebrovascular event, acute limb-ischemia).
Results:
During follow-up 39 of these patients suffered a MACCE. SE correctly identified 33 of these 39 patients by demonstrating silent ischemia in advance. In a multivariate logistic regression analysis a positive SE turned out to be an independent predictor for the occurrence of a MACCE during 11+/-2 months.
Conclusions:
SE represents an effective tool for risk stratification of asymptomatic DM2 patients.
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