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Updated: Jul 10, 2026

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
Published on: September 8, 2023
Evaluation of bone height and bone density after tooth extraction: an experimental study in minipigs
Paula Vanessa Pedron Oltramari1, Ricardo de Lima Navarro, José Fernando Castanha Henriques
1Department of Orthodontics, Bauru Dental School, University of Sao Paulo, Bauru, Brazil.
Objective:
The objective of this study was to radiographically quantify bone density and bone height preservation in tooth extraction alveolus filled with xenograft.
Study Design:
The maxillary and mandibular fourth deciduous molars and fourth premolars of 6 minipigs were removed. Randomly, in 3 animals the right side was used as the test side and in the other 3 animals the left side was the test side. Intraoral radiographs were performed to compare the condition at the initial time and 3 months later. Measurements of bone height and bone density were performed using KS300 (Zeiss) software.
Results:
After 3 months, there was a statistically significant smaller bone height loss for the test group. The test group presented a statistically greater bone density immediately after tooth extraction. However, after 3 months there was no statistically significant difference between the groups.
Conclusions:
The results suggest that treatment of postextraction alveolus with xenograft can preserve bone height initially but differences in bone density compared to when no xenograft is used are not sustained.

