Varicose vein stripping vs haemodynamic correction (CHIVA): a long term randomised trial
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S Carandina1, C Mari, M De Palma
1Department of Surgical, Anaesthesiological, and Radiological Sciences, Day-Surgery Unit, Vascular Diseases Center, University of Ferrara, Italy.
Insights
Saphenous stripping resulted in higher varicose vein recurrence rates compared to Ambulatory Conservative Haemodynamic Management of Varicose Veins (CHIVA) over ten years. CHIVA preserves venous drainage, potentially reducing recurrence in chronic venous disease.
Area of Science:
- Vascular Surgery
- Phlebology
- Medical Technology Assessment
Background:
- Superficial venous incompetence leads to chronic venous disease (CVD).
- Traditional saphenous vein stripping is a common treatment for CVD.
- Alternative minimally invasive techniques are being explored to improve long-term outcomes.
Purpose of the Study:
- To compare the long-term efficacy of saphenous vein stripping versus CHIVA.
- To evaluate recurrence rates and clinical outcomes in patients with CVD.
- To assess the impact of treatment on superficial venous incompetence.
Main Methods:
- A randomized comparative trial involving 150 patients with CVD (CEAP class 2-6).
- Patients were randomized to either saphenous stripping or CHIVA treatment.
- Clinical outcomes (Hobbs score), subjective patient reports, and recurrence (clinical/ultrasound) were assessed over a mean 10-year follow-up.
Main Results:
- No significant difference in the Hobbs clinical score between stripping and CHIVA groups.
- Varicose vein recurrence was significantly higher in the stripping group (35%) compared to CHIVA (18%, P<0.04).
- The risk of recurrence at ten years was doubled in the stripping group (OR 2.2).
Conclusions:
- Saphenous stripping leads to a higher frequency of recurrent varicose veins compared to CHIVA.
- CHIVA treatment, by preserving the saphenous trunk for venous drainage, may reduce recurrence rates.
- CHIVA represents a potentially more effective long-term treatment strategy for superficial venous incompetence.
Objectives:
To compare the long-term results of stripping vs. haemodynamic correction (Ambulatory Conservative Haemodynamic Management of Varicose Veins, CHIVA) in the treatment of superficial venous incompetence resulting in chronic venous disease (CVD).
Design:
Randomised comparative trial.
Patients:
150 patients affected by CVD, CEAP clinical class 2-6, were randomised to saphenous stripping or to CHIVA.
Methods:
The clinical outcome was assessed by an independent observer who recorded the Hobbs clinical score for treated limbs. A subjective report of the outcome was provided by the patients. Recurrence of varices was assessed by both clinical examination and duplex ultrasonography.
Results:
The mean follow-up was 10 years, 26 patients were lost to follow-up. The Hobbs score similar in the stripping and CHIVA groups. However recurrence of varicose veins was significantly higher in the stripping group (CHIVA 18%; stripping 35%, P<0.04 Fisher's exact test), without significant differences in the rate of recurrences from the sapheno-femoral junction. The associated risk of recurrence at ten years was doubled in the stripping group (OR 2.2, 95% CI 1-5, P=0.04).
Conclusions:
Recurrent varices occurred more frequently following saphenous stripping than after CHIVA treatment. The deliberate preservation of the saphenous trunk as a route of venous drainage in the CHIVA group may have been a factor reducing the recurrence rate.
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