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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Related Experiment Video

Updated: Jul 10, 2026

Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET
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[Therapeutic response evaluation by nuclear functional imaging].

Jean-Luc Moretti1, Elif Hindie, Laetitia Vercellino

  • 1Médecine Nucléaire, CHU Saint-Louis, 1 avenue Claude-Vellefaux, 75475 Paris Cedex. jean-luc.moretti@sls.aphp.fr

Bulletin Du Cancer
|November 6, 2007
PubMed
Summary
This summary is machine-generated.

Nuclear functional imaging reliably evaluates cancer treatments early. This technique is crucial for developing and validating new targeted anti-tumor therapies.

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Area of Science:

  • Oncology
  • Nuclear Medicine
  • Radiochemistry

Background:

  • Nuclear functional imaging offers early assessment of conventional chemotherapy.
  • It is instrumental in the research and development of novel anti-cancer agents.

Purpose of the Study:

  • To highlight the role of nuclear functional imaging in evaluating anti-tumor therapies.
  • To emphasize its utility in the validation of targeted cancer treatments.

Main Methods:

  • Review of nuclear functional imaging techniques.
  • Analysis of their application in preclinical and clinical studies.
  • Focus on cytotoxic, cytostatic, and targeted therapy evaluation.

Main Results:

  • Nuclear functional imaging provides reliable early assessment of treatment response.
  • It is a key tool for validating the efficacy of targeted anti-cancer drugs.
  • Demonstrates potential for personalized medicine approaches in oncology.

Conclusions:

  • Nuclear functional imaging is essential for the early evaluation of conventional and targeted cancer therapies.
  • Its role is critical in the development and validation pipeline for new anti-tumor agents.
  • Supports the advancement of precision oncology through reliable treatment assessment.