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Delirium post-stroke.

John McManus1, Rohan Pathansali, Rob Stewart

  • 1Department of Clinical Gerontology, Clinical Age Research Unit, King's College Hospital NHS Foundation Trust, Denmark Hill, Bessemer Road, London SE5 9PJ, UK. jmcmanus2001@hotmail.com

Age and Ageing
|October 30, 2007
PubMed
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Delirium is a common and serious complication in older patients after hospital admission, particularly following a stroke. This review examines the current literature on delirium in acute stroke patients, highlighting knowledge gaps and prognostic implications.

Area of Science:

  • Neurology
  • Geriatrics
  • Critical Care Medicine

Background:

  • Delirium is a frequent and severe complication in hospitalized older adults.
  • Stroke is a known risk factor for delirium, but existing research presents conflicting prevalence data (13-48%).
  • The underlying causes and optimal screening methods for post-stroke delirium remain unclear.

Purpose of the Study:

  • To review the existing literature on delirium in the acute stroke setting.
  • To identify specific stroke types and lesion locations associated with delirium.
  • To highlight the prognostic implications and lack of intervention data for post-stroke delirium.

Main Methods:

  • Literature review of studies on delirium in acute stroke patients.
  • Analysis of reported prevalence rates and associated factors.

Related Experiment Videos

  • Examination of prognostic outcomes and intervention strategies.
  • Main Results:

    • Prevalence of delirium post-stroke varies widely (13-48%) with conflicting findings.
    • Certain stroke types (e.g., intracerebral hemorrhage, TACI) and specific lesions (e.g., thalamus, caudate nucleus) may increase risk.
    • Delirium post-stroke is linked to adverse outcomes: longer hospital stays, higher mortality, and increased institutionalization.

    Conclusions:

    • Delirium is a significant complication of stroke with serious prognostic implications.
    • Further research is needed to understand the etiology, improve screening, and develop interventions for post-stroke delirium.
    • Addressing delirium in acute stroke patients is crucial for improving patient outcomes.