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Higher heart rate predicts the risk of developing hypertension in a normotensive screened cohort

Taku Inoue1, Kunitoshi Iseki, Chiho Iseki

  • 1Cardiovascular Division, Heart Life Hospital, Okinawa, Japan. imtak-ryk@umin.ac.jp

Circulation Journal : Official Journal of the Japanese Circulation Society
|October 30, 2007
PubMed

Insights

Higher resting heart rate (HR) is linked to increased risk of developing hypertension in adults. Even if blood pressure is normal, elevated HR warrants careful monitoring for cardiovascular health.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Public Health

Background:

  • Elevated heart rate (HR) is a known risk factor for cardiovascular morbidity and mortality.
  • Hypertension is a significant contributor to cardiovascular disease.
  • The relationship between higher HR and hypertension development in normotensive individuals requires investigation.

Purpose of the Study:

  • To determine if a higher resting heart rate (HR) is associated with the future development of hypertension.
  • To assess the incidence of hypertension in relation to baseline HR quartiles among initially normotensive subjects.

Main Methods:

  • A cohort of 4,331 initially normotensive adults was followed for 3 years.
  • Participants were categorized into four groups based on their resting heart rate (HR) in 1997.
  • Logistic regression analysis was used to adjust for various cardiovascular risk factors and lifestyle variables.

Main Results:

  • The incidence of developing hypertension over 3 years was significantly higher in individuals with higher baseline HR quartiles.
  • Individuals in the highest HR quartile had a 1.61 times greater odds of developing hypertension compared to the lowest quartile.
  • Higher HR was also associated with more metabolic syndrome components and increased proteinuria.

Conclusions:

  • A higher resting heart rate (HR) is a significant predictor for the development of hypertension.
  • Individuals with elevated HR, even when normotensive, require close medical observation for early detection of hypertension.
Abstract

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