Related Experiment Video
Updated: Jul 10, 2026
A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
Published on: November 15, 2024
Reversible diffusion-weighted imaging changes in the splenium of the corpus callosum and internal capsule associated
Yuzo Terakawa1, Naohiro Tsuyuguchi, Katsuyuki Nunomura
1Department of Neurosurgery, Osaka City University Graduate School of Medicine, Osaka, Japan. terakawa@msic.med.osaka-cu.ac.jp
Abstract:
A 63-year-old man presented with hypoglycemia-induced hemiparesis manifesting as diffusion-weighted magnetic resonance (MR) imaging changes in the splenium of the corpus callosum and internal capsule which disappeared after glucose administration. Clinicians should be aware that hypoglycemia can cause reversible splenium abnormalities on MR imaging, although the underlying mechanism still remains unclear, as this may be helpful in the differential diagnosis of hypoglycemia-induced hemiparesis and stroke.
