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[Simultaneous occurrence of Crohn's and Bechterew's disease]
1Okresní ústav národního zdraví Rychnov nad Knĕznou.
Insights
This case study highlights a 10-year gap between the onset of ankylosing spondylitis (HLA B27 positive) and Crohn's disease. Early detection is crucial for managing these interconnected inflammatory conditions.
Area of Science:
- Rheumatology
- Gastroenterology
- Immunology
Background:
- Ankylosing spondylitis (Bekhterev's disease) is an inflammatory condition often associated with HLA B27.
- Crohn's disease is a chronic inflammatory bowel disease affecting the digestive tract.
- Extraintestinal manifestations are common in Crohn's disease.
Abstract:
The author describes a case-history of concomitant manifestation of classical Bekhterev's disease (HLA B 27 positive) which preceded by 10 years the detection of Crohn's disease of the stomach, terminal ileum and rectum. The author discusses the relationship of the two diseases in particular with regard to the probable defined extraintestinal manifestation of Crohn's disease. The concurrent presence of the two diseases causes difficulties when assessing the humoral activity. For ankylosing spondylarthritis with a manifest or silent intestinal inflammation 5-aminosalicylic acid is the drug of choice. Early detection of the two diseases is important for therapy and prognosis.