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Related Concept Videos

Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

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Related Experiment Video

Updated: Jul 10, 2026

Experimental Model to Evaluate Resolution of Pneumonia
09:49

Experimental Model to Evaluate Resolution of Pneumonia

Published on: February 17, 2023

[Fever, pneumonia and eosinophilia].

D Berger1, W Pichler, S Savic

  • 1Medizinische Klinik, Bürgerspital Solothurn.

Praxis
|October 31, 2007
PubMed
Summary

A 71-year-old man developed acute eosinophilic pneumonia, a serious lung condition. Mefenamic acid, a non-steroidal anti-inflammatory drug, was identified as the likely cause through diagnostic testing.

Area of Science:

  • Pulmonology
  • Allergology
  • Clinical Pharmacology

Background:

  • Acute eosinophilic pneumonia (AEP) is a rare but severe lung disease.
  • Drug-induced hypersensitivity is an important differential diagnosis for AEP.

Observation:

  • A 71-year-old male presented with symptoms suggestive of acute eosinophilic pneumonia.
  • Extensive investigations ruled out common causes of AEP.
  • A positive lymphocyte transformation test implicated mefenamic acid.

Findings:

  • Mefenamic acid, a non-steroidal anti-inflammatory drug (NSAID), was identified as the probable causative agent.
  • The patient's condition was consistent with a drug-induced allergic reaction manifesting as AEP.

Implications:

Related Experiment Videos

Last Updated: Jul 10, 2026

Experimental Model to Evaluate Resolution of Pneumonia
09:49

Experimental Model to Evaluate Resolution of Pneumonia

Published on: February 17, 2023

  • This case highlights the importance of considering NSAIDs in the differential diagnosis of AEP.
  • Early identification and withdrawal of the offending drug are crucial for managing drug-induced AEP.
  • Awareness of NSAID-induced pulmonary reactions can prevent potentially life-threatening outcomes.